Identifying a gene-regulatory network that drives fibromuscular dysplasia

Fibromuscular dysplasia (FMD) is a poorly understood blood vessel disorder that affects up to 5% of adults. Using a systems genetics approach, we identified an FMD-associated gene

co-expression network that governs vascular cell function and developed a mouse model of FMD that recapitulates certain aspects of the human disease. Access through your institution Buy or

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COMPLEX DISEASES. CAS  PubMed  PubMed Central  Google Scholar  Download references ADDITIONAL INFORMATION PUBLISHER’S NOTE Springer Nature remains neutral with regard to jurisdictional

claims in published maps and institutional affiliations. THIS IS A SUMMARY OF: d’Escamard, V. et al. Integrative gene regulatory network analysis discloses key driver genes of fibromuscular

dysplasia. _Nat. Cardiovasc. Res_. https://doi.org/10.1038/s44161-024-00533-w (2024). RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Identifying a

gene-regulatory network that drives fibromuscular dysplasia. _Nat Cardiovasc Res_ 3, 1033–1034 (2024). https://doi.org/10.1038/s44161-024-00534-9 Download citation * Published: 13 September

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