Early rheumatoid arthritis: combination therapy of doxycycline plus methotrexate versus methotrexate monotherapy

Access through your institution Buy or subscribe boxed-textO'Dell JR _ et al_. (2006) Treatment of early seropositive rheumatoid arthritis. Doxycycline plus methotrexate versus

methotrexate alone. _Arthritis Rheum_ 54: 621–627 Clinicians should consider doxycycline in combination with methotrexate for the treatment of patients with early rheumatoid arthritis This

is a preview of subscription content, access via your institution RELEVANT ARTICLES Open Access articles citing this article. * GENETIC VARIATIONS IN METHOTREXATE METABOLIC PATHWAY GENES

INFLUENCE METHOTREXATE RESPONSES IN RHEUMATOID ARTHRITIS PATIENTS IN MALAYSIA * Hong Xi Sha * , Kumar Veerapen *  … Jung Shan Hwang _Scientific Reports_ Open Access 13 July 2022 ACCESS

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institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * O'Dell JR _ et al_. (1996) Treatment of rheumatoid arthritis with methotrexate alone, sulfasalazine

and hydroxychloroquine, or a combination of all three medications. _N Engl J Med_ 334: 1287–1291 Article  CAS  Google Scholar  * O'Dell JR _ et al_. (2000) Early sero-positive

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beneficial in rheumatoid arthritis, but not for the reasons that you think. _J Clin Rheumatol_ 3: 190–193 Google Scholar  Download references ACKNOWLEDGEMENTS The synopsis was written by

Jasmine Farsarakis, Associate Editor, Nature Clinical Practice. AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Jane Knight Lowe Chair of Medicine in Rheumatology at the University of Alabama

at Birmingham, Birmingham, Alabama, USA Graciela S Alarcón Authors * Graciela S Alarcón View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING

AUTHOR Correspondence to Graciela S Alarcón. ETHICS DECLARATIONS COMPETING INTERESTS The author declares no competing financial interests. RIGHTS AND PERMISSIONS Reprints and permissions

ABOUT THIS ARTICLE CITE THIS ARTICLE Alarcón, G. Early rheumatoid arthritis: combination therapy of doxycycline plus methotrexate versus methotrexate monotherapy. _Nat Rev Rheumatol_ 2,

296–297 (2006). https://doi.org/10.1038/ncprheum0195 Download citation * Received: 06 March 2006 * Accepted: 10 April 2006 * Issue Date: June 2006 * DOI: https://doi.org/10.1038/ncprheum0195

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