
Preliminary study says covishield effective against ‘double mutant’ coronavirus
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Though B.1.617 is called 'double mutant', it is characterised by more than 15 mutations. "It got dubbed the 'double mutant' because of two spike mutations, L452R and
E484Q, which were mutations of concern because of their immune escape properties, and possible high infectivity," wrote Sowpati, who is leading COVID-19 genomics at CCMB.