Locmofit quantifies cellular structures in super-resolution data

Locmofit quantifies cellular structures in super-resolution data


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Localization Model Fit (LocMoFit) is a tool that enables fitting of super-resolution microscopy data to an arbitrary geometric model. The fit extracts quantitative parameters of individual


cellular structures, which can be used to investigate dynamic and heterogenous protein assemblies and to create average protein distribution maps. Access through your institution Buy or


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ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Liu, S., Hoess, P. & Ries, J. Super-resolution


microscopy for structural cell biology. _Annu. Rev. Biophys._ 51, 301–326 (2022). A COMPREHENSIVE REVIEW THAT SUMMARIZES THE APPLICATIONS OF SUPER-RESOLUTION MICROSCOPY IN STRUCTURAL CELL


BIOLOGY. Article  Google Scholar  * Wu, Y.-L., Tschanz, A., Krupnik, L. & Ries, J. Quantitative data analysis in single-molecule localization microscopy. _Trends Cell Biol._ 30, 837–851


(2020). A REVIEW ARTICLE THAT SUMMARIZES CURRENT QUANTITATIVE DATA ANALYSIS APPROACHES IN SINGLE-MOLECULE LOCALIZATION MICROSCOPY. Article  CAS  Google Scholar  * Ries, J. SMAP: a modular


super-resolution microscopy analysis platform for SMLM data. _Nat. Methods_ 17, 870–872 (2020). THIS IS AN OVERVIEW OF OUR SUPER-RESOLUTION MICROSCOPY ANALYSIS PLATFORM, WHICH PROVIDES EASY


ACCESS TO LOCMOFIT. Article  CAS  Google Scholar  * Mund, M. et al. Super-resolution microscopy reveals partial preassembly and subsequent bending of the clathrin coat during endocytosis.


Preprint at _bioRxiv_ https://doi.org/10.1101/2021.10.12.463947 (2021). THIS PREPRINT PAPER REPORTS A REAL-LIFE APPLICATION OF LOCMOFIT TO ANSWER BIOLOGICAL QUESTIONS. Download references


ADDITIONAL INFORMATION PUBLISHER’S NOTE Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. THIS IS A SUMMARY OF: Wu, Y.-L.


et al. Maximum-likelihood model fitting for quantitative analysis of SMLM data. _Nat. Methods_ https://doi.org/10.1038/s41592-022-01676-z (2022). RIGHTS AND PERMISSIONS Reprints and


permissions ABOUT THIS ARTICLE CITE THIS ARTICLE LocMoFit quantifies cellular structures in super-resolution data. _Nat Methods_ 20, 44–45 (2023). https://doi.org/10.1038/s41592-022-01696-9


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