Legionella dismantles linear ubiquitin

Host cells assemble linear ubiquitin chains to activate immune signalling during bacterial infection. A new study reveals that _Legionella pneumophila_ — the causative agent of Legionnaires’

disease — produces an enzyme that specifically disassembles these linear ubiquitin modifications to restrict immune responses. Access through your institution Buy or subscribe This is a

preview of subscription content, access via your institution RELEVANT ARTICLES Open Access articles citing this article. * INSIGHTS INTO UBIQUITINOME DYNAMICS IN THE HOST‒PATHOGEN INTERPLAY

DURING FRANCISELLA NOVICIDA INFECTION * Luyu Yang * , Yanfeng Li *  … Xiaopeng Qi _Cell Communication and Signaling_ Open Access 18 October 2024 ACCESS OPTIONS Access through your

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_Nat. Cell Biol._ 12, 66–73 (2010). Article  CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Medical Research Council Laboratory of Molecular Biology,

Cambridge, UK Rune Busk Damgaard * Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, OR, USA Jonathan N. Pruneda Authors * Rune Busk

Damgaard View author publications You can also search for this author inPubMed Google Scholar * Jonathan N. Pruneda View author publications You can also search for this author inPubMed 

Google Scholar CORRESPONDING AUTHORS Correspondence to Rune Busk Damgaard or Jonathan N. Pruneda. ETHICS DECLARATIONS COMPETING INTERESTS The authors declare no competing interests. RIGHTS

AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Damgaard, R.B., Pruneda, J.N. _Legionella_ dismantles linear ubiquitin. _Nat Microbiol_ 4, 1244–1245 (2019).

https://doi.org/10.1038/s41564-019-0515-5 Download citation * Published: 23 July 2019 * Issue Date: August 2019 * DOI: https://doi.org/10.1038/s41564-019-0515-5 SHARE THIS ARTICLE Anyone you

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