The reprogramming method matters

The genetic, epigenetic and transcriptomic profiles of human induced pluripotent stem cells are shaped by the reprogramming route. Access through your institution Buy or subscribe This is a

preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value

online-access subscription $32.99 / 30 days cancel any time Learn more Subscribe to this journal Receive 12 digital issues and online access to articles $119.00 per year only $9.92 per issue

Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL

ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support CHANGE HISTORY * _ 02 JANUARY 2018 In the version of this News and Views article

originally published, an erroneous hyphen was included in the term ‘human-induced pluripotent stem cells’; it should have read ‘human induced pluripotent stem cells’. This error has now

been corrected in all versions of the News and Views article. _ REFERENCES * Takahashi, K. et al. _Cell_ 131, 861–872 (2007). Article  CAS  PubMed  Google Scholar  * Bock, C. et al. _Cell_

144, 439–452 (2011). Article  CAS  PubMed  PubMed Central  Google Scholar  * Chin, M., Mason, M., Xie, W., Volinia, S. & Singer, M. _Cell Stem Cell_ 5, 111–123 (2009). Article  CAS 

PubMed  PubMed Central  Google Scholar  * Ruiz, S. et al. _Proc. Natl Acad. Sci. USA_ 109, 16196–16201 (2012). Article  CAS  PubMed  PubMed Central  Google Scholar  * Churko, J. M. et al.

_Nat. Biomed. Eng._ https://doi.org/10.1038/s41551-017-0141-6 (2017). Article  Google Scholar  * Amps, K. et al. _Nat. Biotech_ 29, 1132–1144 (2011). Article  CAS  Google Scholar  * Baker,

D. et al. _Stem Cell Rep_ 7, 998–1012 (2016). Article  CAS  Google Scholar  * Huangfu, D. et al. _Nat. Biotechnol._ 26, 795–797 (2008). Article  CAS  PubMed  Google Scholar  Download

references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095,

USA Thomas F. Allison * Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, 90095, USA Thomas F. Allison & William E. Lowry

* Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA, 90095, USA William E. Lowry * Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell

Research, University of California, Los Angeles, Los Angeles, CA, 90095, USA Thomas F. Allison & William E. Lowry * Department of Dermatology, David Geffen School of Medicine, University

of California, Los Angeles, Los Angeles, CA, 90095, USA William E. Lowry * Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, Los

Angeles, CA, 90095, USA William E. Lowry Authors * Thomas F. Allison View author publications You can also search for this author inPubMed Google Scholar * William E. Lowry View author

publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to William E. Lowry. ADDITIONAL INFORMATION A correction to this article is

available online at https://doi.org/10.1038/s41551-017-0170-1. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Allison, T.F., Lowry, W.E. The

reprogramming method matters. _Nat Biomed Eng_ 1, 779–781 (2017). https://doi.org/10.1038/s41551-017-0148-z Download citation * Published: 10 October 2017 * Issue Date: October 2017 * DOI:

https://doi.org/10.1038/s41551-017-0148-z SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not

currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative