Correction: ceacam1 impedes thyroid cancer growth but promotes invasiveness: a putative mechanism for early metastases

Correction: ceacam1 impedes thyroid cancer growth but promotes invasiveness: a putative mechanism for early metastases


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Correction to: _Oncogene_ https://doi.org/10.1038/sj.onc.1210077, published online 23 October 2006 The authors are issuing a correction for the above article. In Figure 1a, b, the original


experiments included the DRO cell line which was thought to be a thyroid cancer cell line. At the time of publication in 2006, the authors had just been informed that DRO cells were not


thyroid cancer. This information was subsequently published (Schweppe RE et al., J. Clin. Endocrinol. Metab. 2008 93:4331–4341 originally published online Aug 19, 2008;


https://doi.org/10.1210/jc.2008-1102). On receiving this information immediately prior to submission of the manuscript, the authors removed the data on the DRO cells. Figure 1a, b are being


replaced by the original data with the recognition that DRO cells are not thyroid cancer cells. The overall results and conclusions are not affected by the change. FIGURE 1A, B. CEACAM1 IS


EXPRESSED IN HUMAN THYROID CARCINOMA-DERIVED CELL LINES. (A) RNA extracted from human thyroid carcinoma-derived cell lines as well as the DRO cell line was PCR-amplified using primers for


CEACAM1. Products consistent with CEACAM1-L (408 bp) and the shorter CEACAM1-S (355 bp) form were identified in ARO anaplastic and MRO follicular carcinoma cells. The lower panel represents


the PGK-1 control. Each lane is followed by the same reaction with omission of the reverse transcriptase. (B) Western immunoblotting of corresponding cell lysates demonstrates CEACAM1


expression in the ARO and MRO cell lines. The actin control is shown below. During investigation of this paper in 2016, the original blots for actin in Figure 2a could not be found. However,


the blots for CEACAM1 include the residual loading control for actin in the lower bands as shown here. These clearly show the appropriate loading of protein, confirming the accuracy of the


data. FIGURE 2A. CEACAM1 IMPACTS DIFFERENT PARAMETERS OF THYROID CANCER CELL GROWTH. Forced expression of CEACAM1 in deficient WRO cells (left) and downregulation using stable siRNA in


CEACAM1-expressing MRO cells (right) was established in multiple stable clones. AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Pathology, University Health Network and Toronto


Medical Laboratories, Toronto, ON, Canada W. Liu, W. Wei, D. Winer & S. L. Asa * Ontario Cancer Institute and University of Toronto, Toronto, ON, Canada W. Liu, W. Wei, D. Winer, S.


Ezzat & S. L. Asa * Department of Pathology, University Hospital Hamburg Eppendorf, Toronto, ON, Canada A. -M Bamberger * Department of Internal Medicine, University Hospital Hamburg


Eppendorf, Toronto, ON, Canada C. Bamberger * Department of Clinical Chemistry, University Hospital Hamburg Eppendorf, Toronto, ON, Canada C. Wagener * Department of Medicine, Mount Sinai


Hospital, Toronto, ON, Canada S. Ezzat Authors * W. Liu View author publications You can also search for this author inPubMed Google Scholar * W. Wei View author publications You can also


search for this author inPubMed Google Scholar * D. Winer View author publications You can also search for this author inPubMed Google Scholar * A. -M Bamberger View author publications You


can also search for this author inPubMed Google Scholar * C. Bamberger View author publications You can also search for this author inPubMed Google Scholar * C. Wagener View author


publications You can also search for this author inPubMed Google Scholar * S. Ezzat View author publications You can also search for this author inPubMed Google Scholar * S. L. Asa View


author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to S. L. Asa. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS


ARTICLE CITE THIS ARTICLE Liu, W., Wei, W., Winer, D. _et al._ Correction: CEACAM1 impedes thyroid cancer growth but promotes invasiveness: a putative mechanism for early metastases.


_Oncogene_ 42, 3159–3160 (2023). https://doi.org/10.1038/s41388-023-02833-0 Download citation * Published: 13 September 2023 * Issue Date: 13 October 2023 * DOI:


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