Effect of patient gender on short-term blood pressure variability in hemodialysis patients

ABSTRACT Increased blood pressure variability (BPV) is strongly associated with cardiovascular events in end-stage kidney disease patients. Male hemodialysis patients present higher

cardiovascular risk compared with females. The aim of this study is to investigate sex differences in short-term BPV in hemodialysis patients. 129 male and 91 female hemodialysis patients

that underwent 48-h ABPM were included in this analysis. Standard deviation (SD), weighted SD (wSD), coefficient of variation (CV), and average real variability (ARV) of SBP and DBP were

calculated with validated formulas. Age, dialysis vintage and history of major comorbidities did not differ between men and women. 48-h SBP/DBP (137.2 ± 17.4/81.9 ± 12.1 mmHg vs 132.2 ± 

19.2/75.9 ± 11.7 mmHg, _p_ = 0.045/<0.001) was significantly higher in men than women. During the 48-h period, all systolic BPV indices were similar between men and women (48-h SBP-ARV:

12.0 ± 2.9 vs 12.1 ± 3.2 mmHg, _p_ = 0.683); 48-h DBP-SD, DBP-wSD and DBP-ARV (9.1 ± 1.6 vs 8.4 ± 1.8 mmHg, _p_ = 0.005) were higher in men. In conclusion, short-term diastolic BPV indices

are higher in male than female hemodialysis patients. Increased BPV may impact on the higher incidence of cardiovascular events observed in male hemodialysis patients. Access through your

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SIMILAR CONTENT BEING VIEWED BY OTHERS BLOOD PRESSURE VARIABILITY IN CKD PATIENTS WITH AND WITHOUT NOCTURNAL HYPERTENSION Article 28 February 2025 ACCURACY OF 24 H AMBULATORY BLOOD PRESSURE

RECORDINGS FOR DIAGNOSING HIGH 44 H BLOOD PRESSURE IN HEMODIALYSIS: A DIAGNOSTIC TEST STUDY Article 30 January 2024 DIALYSATE SODIUM AND SHORT-TERM BLOOD PRESSURE VARIABILITY IN PATIENTS

WITH INTRADIALYTIC HYPERTENSION: A RANDOMIZED CROSSOVER STUDY Article 24 August 2024 DATA AVAILABILITY The datasets generated during and/or analysed during the current study are available

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Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Nephrology, Hippokration Hospital, Aristotle University, Thessaloniki, Greece Marieta P.

Theodorakopoulou, Maria-Eleni Alexandrou, Artemios G. Karagiannidis, Virginia Geladari, Georgia Polychronidou, Aikaterini Papagianni & Pantelis Sarafidis Authors * Marieta P.

Theodorakopoulou View author publications You can also search for this author inPubMed Google Scholar * Maria-Eleni Alexandrou View author publications You can also search for this author

inPubMed Google Scholar * Artemios G. Karagiannidis View author publications You can also search for this author inPubMed Google Scholar * Virginia Geladari View author publications You can

also search for this author inPubMed Google Scholar * Georgia Polychronidou View author publications You can also search for this author inPubMed Google Scholar * Aikaterini Papagianni View

author publications You can also search for this author inPubMed Google Scholar * Pantelis Sarafidis View author publications You can also search for this author inPubMed Google Scholar

CONTRIBUTIONS Research idea and study design: MT, PS; data acquisition: AK, VG, GP; statistical analysis: MT, MA; data analysis and interpretation: MT, MA, PS; manuscript drafting: MT, PS;

supervision/mentorship: AP, PS. CORRESPONDING AUTHOR Correspondence to Pantelis Sarafidis. ETHICS DECLARATIONS COMPETING INTERESTS The authors declare no competing interests. ETHICAL

APPROVAL The study protocol was approved by the Ethics Committee of School of Medicine, Aristotle University of Thessaloniki and all evaluations were performed according to the Declaration

of Helsinki (2013 Amendment). ADDITIONAL INFORMATION PUBLISHER’S NOTE Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Theodorakopoulou, M.P., Alexandrou, ME., Karagiannidis, A.G. _et al._ Effect of patient gender on

short-term blood pressure variability in hemodialysis patients. _J Hum Hypertens_ 37, 519–523 (2023). https://doi.org/10.1038/s41371-022-00725-6 Download citation * Received: 28 March 2022 *

Revised: 23 June 2022 * Accepted: 05 July 2022 * Published: 16 July 2022 * Issue Date: July 2023 * DOI: https://doi.org/10.1038/s41371-022-00725-6 SHARE THIS ARTICLE Anyone you share the

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