Fecal cytotoxin on vero cells (vt) and circulating vt1 antibodies in the idiopathic hemolytic uremic syndrome (hus), compared with family members living together (fm) and controls with family diarrhea (c)

ABSTRACT Between January and July 1988, 14 children with HUS, 28 FM and 12 C were investigated. Mean age of HUS was, 11.9 months(3 - 36) and of C, 7.5 months (3-15). In both groups sex

distribution was 50%. The prodromal illness in HUS was characterized by diarrhea in 100%, bloody stools in 85.7% and upperrespiratory tract symptoms in 21.4%. Laboratory data in HUS and C

respectively were: hematocrit 22% (13-29) and 34 (28-41); leukocytes, 23,170 (8,800-91,000) and 10,700 (7,800-14,300). Platelet count, 92,000 (10,000-200,000) and 287,000 (170,000-650,000);

blood urea, 161mg% (40-290) and 22 (10-61); serum creatinine, 3.5mg% (0.8-7.8) and 0.54 (0.45-0.81). In HUS red blood cell transfusion and peritoneal dialysis was respectively required in

78.6% and 42.9% of the cases. First samples were obtained in HUS at mean of 9.6 days (4-27) and in C at 5.8 days (2-16) after the onset of acute diarrhea. 42.8% of HUS and none of C had

reveived previous antibiotic treatment. Fecal VT was detected in 10 HUS (71.4%) in 4 FM (14.3%) and in 1 C (8.3%; p<0.01). Specific neutralization of VT1 was obtained in 6 HUS, 1 FM and 1

C. Circulating VT1 neutralizing antibodies were detected in 1 HUS, 2 FM and 1 C. ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Hospital Genal de Ninos Pedro de Elizalde.

Instituto Nacional de Microbiologia C. Malrán, Buenos Aires, Argentina L Voyer, M Rivas, M Tous, C Iriarte, S Corti & S Santaroangelo Authors * L Voyer View author publications You can

also search for this author inPubMed Google Scholar * M Rivas View author publications You can also search for this author inPubMed Google Scholar * M Tous View author publications You can

also search for this author inPubMed Google Scholar * C Iriarte View author publications You can also search for this author inPubMed Google Scholar * S Corti View author publications You

can also search for this author inPubMed Google Scholar * S Santaroangelo View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints

and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Voyer, L., Rivas, M., Tous, M. _et al._ FECAL CYTOTOXIN ON VERO CELLS (VT) AND CIRCULATING VT1 ANTIBODIES IN THE IDIOPATHIC HEMOLYTIC

UREMIC SYNDROME (HUS), COMPARED WITH FAMILY MEMBERS LIVING TOGETHER (FM) AND CONTROLS WITH FAMILY DIARRHEA (C). _Pediatr Res_ 26, 162 (1989). https://doi.org/10.1203/00006450-198908000-00021

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