Structure and filtration performances of improved cuprammonium regenerated cellulose hollow fiber (improved bmm hollow fiber) for virus removal

ABSTRACT To get higher performances of virus removability and permeability of protein than those of the previous cuprammonium regenerated cellulose hollow fiber (referred to as BMM) novel

spinning conditions such as minimerized tension loaded on a fiber in addition to high accurate control of temperature and composition were employed (the novel BMM hollow fiber thus obtained

is referred to as i-BMM). Comprehensive analysis of the pore structure of i-BMM using electron microscope and its filtration characteristics concerning to virus removability and protein

permeability indicated that (1) the degree of orientation of the cellulosic substrate and “voids” in i-BMM to the direction of the fiber axis decreased comparied with that of BMM and this

led to the disappearance of the breakage of the cellulosic wall between neighbouring voids, (2) the size of the capillary of i-BMM was larger than that of BMM, (3) the virus removability of

i-BMM for Japanese encephalitis virus was about 103 times BMM when the comparison was made under the same mean pore size. These indicate that the existence probability of “voids” linking

side by side and penetrating the membrane from the inner to the outer surface decreased for i-BMM and this is the reason i-BMM is superior to BMM in virus removal. SIMILAR CONTENT BEING

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Project, Fibers and Textiles Administration, Asahi Chemical Industry Co., Ltd., Takashi Tsurumi, Tetsuo Sato, Naoki Osawa, Hidetoshi Hitaka, Tomoko Hirasaki, Sei-ichi Manabe & Takashi

Yamashiki * Institute of Laboratory Animals, Yamaguchi University School of Medicine, Kazuhito Yamaguchi * Department of Virology and Parasitology, Yamaguchi University School of Medicine,

Yoshiaki Hamamoto * Department of Microbiology, Tokyo Medical and Dental University School of Medicine, Naoki Yamamoto Authors * Takashi Tsurumi View author publications You can also search

for this author inPubMed Google Scholar * Tetsuo Sato View author publications You can also search for this author inPubMed Google Scholar * Naoki Osawa View author publications You can also

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publications You can also search for this author inPubMed Google Scholar * Kazuhito Yamaguchi View author publications You can also search for this author inPubMed Google Scholar * Yoshiaki

Hamamoto View author publications You can also search for this author inPubMed Google Scholar * Sei-ichi Manabe View author publications You can also search for this author inPubMed Google

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inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Tsurumi, T., Sato, T., Osawa, N. _et al._ Structure and Filtration Performances

of Improved Cuprammonium Regenerated Cellulose Hollow Fiber (Improved BMM Hollow Fiber) for Virus Removal. _Polym J_ 22, 1085–1100 (1990). https://doi.org/10.1295/polymj.22.1085 Download

citation * Issue Date: 01 December 1990 * DOI: https://doi.org/10.1295/polymj.22.1085 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get

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Regenerated Cellulose * Hollow Fiber * Electron Micrography * Gold Particle * Virus * Protein