In brief | Nature Reviews Nephrology

Access through your institution Buy or subscribe PRENATAL EXPOSURE TO ALCOHOL REDUCES NEPHRON NUMBER AND RAISES BLOOD PRESSURE IN PROGENY Gray, S. P. _ et al_. _J. Am. Soc. Nephrol._ 21,

1891–1902 (2010) A study in rats reports that prenatal exposure to alcohol is associated with decreased nephron number and increased blood pressure. Gray and colleagues administered ethanol

or saline to pregnant Sprague–Dawley rats on embryonic days 13.5 and 14.5. At 1 month of age, nephron number was 15% lower in alcohol-exposed male progeny and 10% lower in alcohol-exposed

female progeny than in controls. Mean arterial pressure was 10% higher in male and female progeny exposed to alcohol than in controls. This is a preview of subscription content, access via

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Nephrol_ 7, 2 (2011). https://doi.org/10.1038/nrneph.2010.159 Download citation * Published: 20 December 2010 * Issue Date: January 2011 * DOI: https://doi.org/10.1038/nrneph.2010.159 SHARE

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