Advances in motility testing—current and novel approaches

ABSTRACT Disorders of gastrointestinal motility are frequently seen in clinical practice. Apart from motility disorders, factors leading to lowered visceroperception thresholds are

recognized as commonly involved in the pathogenesis of functional gastrointestinal disorders. The wide array of gastrointestinal motility and viscerosensitivity tests available is in

contrast with the relatively limited number of tests used universally in clinical practice. The main reason for this discrepancy is that the outcome of a test only becomes truly important

when it carries clinical consequences. The main goal of this Review is to assess the place of the presently available gastrointestinal motility and sensitivity tests in the clinical

armamentarium of the gastroenterologist. KEY POINTS * High-resolution manometry makes the assessment of oesophageal function easier and provides more information than conventional manometry

* Wireless oesophageal pH monitoring provides an opportunity to assess gastro-oesophageal reflux over prolonged periods of time in a patient-friendly fashion * Intraluminal impedance

monitoring of the oesophagus not only enables detection of nonacid reflux, but can also distinguish different belching types * Wireless motility capsule technology has made it possible to

study gastric emptying, small bowel transit and colonic transit in one noninvasive assessment * Several newly developed investigational tools (such as impedance planimetry and colonic

high-resolution manometry) are promising, but their diagnostic value is not yet clear Access through your institution Buy or subscribe This is a preview of subscription content, access via

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SYNDROME (IBS) AND THEIR RELEVANCE FOR IBS SYMPTOMS Article Open access 17 June 2020 WEARABLE, EPIDERMAL DEVICES FOR ASSESSMENT OF SWALLOWING FUNCTION Article Open access 20 December 2023

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Gastroenterology and Hepatology, Academic Medical Center, Meibergdreef 9, Amsterdam, 1100 DE, the Netherlands Albert J. Bredenoord & André J. P. M. Smout Authors * Albert J. Bredenoord

View author publications You can also search for this author inPubMed Google Scholar * André J. P. M. Smout View author publications You can also search for this author inPubMed Google

Scholar CONTRIBUTIONS The authors contributed equally to all aspects of this article. CORRESPONDING AUTHOR Correspondence to André J. P. M. Smout. ETHICS DECLARATIONS COMPETING INTERESTS A.

J. Bredenoord has received research funding from Shire–Movetis NV and Endostim and received payment from MMS International for development of educational presentations. A. J. P. M. Smout has

received sponsorship from Shire–Movetis NV, MMS international and Given Imaging for an educational meeting on motility testing. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS

ARTICLE CITE THIS ARTICLE Bredenoord, A., Smout, A. Advances in motility testing—current and novel approaches. _Nat Rev Gastroenterol Hepatol_ 10, 463–472 (2013).

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