Pasireotide shows promise for the treatment of acromegaly

Access through your institution Buy or subscribe Pasireotide is a promising novel treatment for acromegaly, according to the findings of a randomized phase II trial. Pasireotide is a

somatostatin analog with high affinity for both somatostatin receptor subtypes (types 2 and 5) expressed by most growth-hormone-secreting pituitary tumors. Consequently, pasireotide has the

potential to be a more effective therapy for acromegaly than the somatostatin analogs octreotide or lanreotide that have low affinity for the type 5 receptor. This is a preview of

subscription content, access via your institution RELEVANT ARTICLES Open Access articles citing this article. * CLINICAL EFFICACY AND SAFETY RESULTS FOR DOSE ESCALATION OF SOMATOSTATIN

RECEPTOR LIGANDS IN PATIENTS WITH ACROMEGALY: A LITERATURE REVIEW * Maria Fleseriu _Pituitary_ Open Access 15 December 2010 ACCESS OPTIONS Access through your institution Subscribe to this

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support ORIGINAL RESEARCH PAPER * Petersenn, S. _ et al_. Pasireotide (SOM230) demonstrates efficacy and safety in patients with acromegaly: a randomized, multicenter, phase II trial. _J.

Clin. Endocrinol. Metab._ 95, 2781–2789 (2010) Article  CAS  PubMed  Google Scholar  Download references Authors * Carol Wilson View author publications You can also search for this author

inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Wilson, C. Pasireotide shows promise for the treatment of acromegaly. _Nat Rev

Endocrinol_ 6, 417 (2010). https://doi.org/10.1038/nrendo.2010.99 Download citation * Issue Date: August 2010 * DOI: https://doi.org/10.1038/nrendo.2010.99 SHARE THIS ARTICLE Anyone you

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