Multiple-laser microplate cytometers: adding a third dimension to high-content screening

ABSTRACT The Acumen® eX3 microplate cytometer is the next generation of the Acumen Explorer® high-content screening system. It is equipped with multiple lasers, offering a wavelength range

for excitation that greatly increases the variety of fluorescent reagents compatible with the system. The Acumen eX3 simplifies assay transfer by combining the powerful object recognition of

charge-coupled device (CCD) imagers with the fast reads of bulk fluorescence readers. Access through your institution Buy or subscribe This is a preview of subscription content, access via

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* Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Bowen, W.P. & Wylie, P.G. Application of laser-scanning fluorescence microplate

cytometry in high content screening. _Assay Drug Dev. Technol._ 4, 209–221 (2006). Article  CAS  Google Scholar  * Auld, D.S. _ et al_. Fluorescence protein-based cellular assays analyzed by

laser scanning microplate cytometry in 1536-well format. _Meth. Enzymol._ (in the press). Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * TTP LabTech Ltd., Melbourn

Science Park, Melbourn, SG8 6EE, Hertfordshire, UK Wayne P Bowen & Sarah L Payne Authors * Wayne P Bowen View author publications You can also search for this author inPubMed Google

Scholar * Sarah L Payne View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Wayne P Bowen. ADDITIONAL INFORMATION

DISCLAIMER This article was submitted to _Nature Methods_ by a commercial organization and has not been peer reviewed. _Nature Methods_ takes no responsibility for the accuracy or otherwise

of the information provided. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Bowen, W., Payne, S. Multiple-laser microplate cytometers: adding a third

dimension to high-content screening. _Nat Methods_ 3, III–IV (2006). https://doi.org/10.1038/nmeth918 Download citation * Published: 23 August 2006 * Issue Date: September 2006 * DOI:

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