How to map billions of short reads onto genomes

How to map billions of short reads onto genomes


Play all audios:

Loading...

Mapping the vast quantities of short sequence fragments produced by next-generation sequencing platforms is a challenge. What programs are available and how do they work? Access through your


institution Buy or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 12 print


issues and online access $209.00 per year only $17.42 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to


local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES *


Nagalakshmi, U. et al. _Science_ 320, 1344–1349 (2008). Article  CAS  Google Scholar  * Mortazavi, A., Williams, B.A., McCue, K., Schaeffer, L. & Wold, B. _Nat. Methods_ 5, 621–628


(2008). Article  CAS  Google Scholar  * Wang, E.T. et al. _Nature_ 456, 470–476 (2008). Article  CAS  Google Scholar  * Johnson, D.S., Mortazavi, A., Myers, R.M. & Wold, B. _Science_


316, 1497–1502 (2007). Article  CAS  Google Scholar  * Ley, T.J. et al. _Nature_ 456, 66–72 (2008). Article  CAS  Google Scholar  * Li, H., Ruan, J. & Durbin, R. _Genome Res._ 18,


1851–1858 (2008). Article  CAS  Google Scholar  * Langmead, B., Trapnell, C., Pop, M. & Salzberg, S.L. _Genome Biol._ 10, R25 (2009). Article  Google Scholar  * Pan, Q., Shai, O., Lee,


L.J., Frey, B.J. & Blencowe, B.J. _Nat. Genet._ 40, 1413–1415 (2008). Article  CAS  Google Scholar  * Trapnell, C., Pachter, L. & Salzberg, S.L. _Bioinformatics_ published online,


doi:10.1093/bioinformatics/btp120 (March 16, 2009). Google Scholar  * Denoeud, F. et al. _Genome Biol._ 9, R175 (2008). Article  Google Scholar  Download references AUTHOR INFORMATION


AUTHORS AND AFFILIATIONS * Cole Trapnell and Steven L. Salzberg are at the Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, USA., Cole


Trapnell & Steven L Salzberg Authors * Cole Trapnell View author publications You can also search for this author inPubMed Google Scholar * Steven L Salzberg View author publications You


can also search for this author inPubMed Google Scholar CORRESPONDING AUTHORS Correspondence to Cole Trapnell or Steven L Salzberg. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT


THIS ARTICLE CITE THIS ARTICLE Trapnell, C., Salzberg, S. How to map billions of short reads onto genomes. _Nat Biotechnol_ 27, 455–457 (2009). https://doi.org/10.1038/nbt0509-455 Download


citation * Issue Date: May 2009 * DOI: https://doi.org/10.1038/nbt0509-455 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link


Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative