Genomes for medicine | Nature

ABSTRACT We have the human genome sequence. It is freely available, accurate and nearly complete. But is the genome ready for medicine? The new resource is already changing genetic research

strategies to find information of medical value. Now we need high-quality annotation of all the functionally important sequences and the variations within them that contribute to health and

disease. To achieve this, we need more genome sequences, systematic experimental analyses, and extensive information on human phenotypes. Flexible and user-friendly access to well-annotated

genomes will create an environment for innovation, and the potential for unlimited use of sequencing in biomedical research and practice. Access through your institution Buy or subscribe

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(2004). Article  Google Scholar  Download references ACKNOWLEDGEMENTS I thank I. Barroso, A. Coffey, T. Cox, S. Grant, T. Hubbard, S. Hunt, G. Leschziner, E. Margulies, K. Rice, J. Rogers,

M. Ross, C. Shaw-Smith, R. Steward, M. Stratton, C. Tyler-Smith and others for assistance, discussion and critical reading of the manuscript. The author is supported financially by the

Wellcome Trust. AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * The Wellcome Trust Sanger Institute, Hinxton, CB10 1SA, Cambridge, UK David R. Bentley Authors * David R. Bentley View author

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