Impact of metabolic syndrome among patients with and without diabetes mellitus on long-term outcomes after percutaneous coronary intervention

ABSTRACT Metabolic syndrome (MS) is highly prevalent and an established key risk factor for coronary artery disease, regardless of the presence or absence of diabetes mellitus (DM).

Long-term follow-up studies have addressed the influence of MS with and without DM on the prognosis of patients undergoing percutaneous coronary intervention (PCI). We classified 748

consecutive patients who had undergone PCI into four groups as follows: neither DM nor MS, DM alone, MS alone, and both DM and MS. Post hoc analyses were conducted using prospectively

collected clinical data. Multivariate Cox regression was used to evaluate the risk within each group for all-cause mortality and composite cardiac events (cardiac death, non-fatal acute

coronary syndrome), adjusting for age, gender, body mass index, low-density lipoprotein (LDL) cholesterol level, hypertension, smoking, prior coronary artery bypass graft, presentation of

acute coronary syndrome, left ventricular ejection fraction, multivessel disease, and procedural success. The progress of 321 (42.9%) patients with neither DM nor MS, 109 (14.6%) patients

with DM alone, 129 (17.2%) patients with MS alone, and 189 (25.3%) patients with both DM and MS was followed up for a mean of 12.0±3.6 years. Patients with both DM and MS had significant

risk for increased all-cause mortality (2.10 [1.19–3.70]). Patients with MS alone (2.14 [1.31–3.50]) and with both DM and MS (1.87 [1.18–2.96]) were at significant risk for increased cardiac

events. In conclusion, the risk of cardiac events is significantly increased in patients with metabolic syndrome following PCI, irrespective of DM. SIMILAR CONTENT BEING VIEWED BY OTHERS

THE ASSOCIATION BETWEEN METABOLIC SYNDROME AND MAJOR ADVERSE CARDIAC AND CEREBROVASCULAR EVENTS IN PATIENTS WITH ACUTE CORONARY SYNDROME UNDERGOING PERCUTANEOUS CORONARY INTERVENTION Article

Open access 06 January 2024 TRIGLYCERIDE TO HIGH DENSITY LIPOPROTEIN CHOLESTEROL RATIO AND MAJOR ADVERSE CARDIOVASCULAR EVENTS IN ACS PATIENTS UNDERGOING PCI Article Open access 30 December

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Cardiology, Juntendo University School of Medicine, Tokyo, Japan Takatoshi Kasai, Katsumi Miyauchi, Takeshi Kurata, Shinya Okazaki, Naozumi Kubota & Hiroyuki Daida * Department of

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THIS ARTICLE Kasai, T., Miyauchi, K., Kurata, T. _et al._ Impact of Metabolic Syndrome among Patients with and without Diabetes Mellitus on Long-Term Outcomes after Percutaneous Coronary

Intervention. _Hypertens Res_ 31, 235–241 (2008). https://doi.org/10.1291/hypres.31.235 Download citation * Received: 03 April 2007 * Accepted: 02 September 2007 * Issue Date: 01 February

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not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative KEYWORDS * coronary artery disease * hypertension * obesity *

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