Kiss-and-tell way to track cell contacts

NEWS AND VIEWS 17 January 2018 Kiss-and-tell way to track cell contacts Transient cellular contacts are essential for the generation of an immune response, but these are difficult to measure

in vivo. A labelling technique now offers a way to record such interactions between cells. By Aaron P. Esser-Kahn0 Aaron P. Esser-Kahn Aaron P. Esser-Kahn is at the Institute for Molecular

Engineering, University of Chicago, Chicago, Illinois 60615, USA.

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Twitter Facebook Email Access through your institution Buy or subscribe Contact between two cells is a key step in the transfer of information during biological processes. However,

monitoring dynamic cellular interactions in vivo poses many technical challenges. In a paper in Nature, Pasqual et al.1 report the development of a technique that can track interactions

between cells that contact each other through receptor–ligand binding.

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Nature 553, 414-415 (2018)

doi: https://doi.org/10.1038/d41586-018-00488-6

References Pasqual, G. et al. Nature 553, 496–500 (2018).

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Liu, D. S., Loh, K. H., Lam, S. S., White, K. A. & Ting, A. Y. PLoS ONE 8, e52823 (2013).

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Mellman, I., Coukos, G. & Dranoff, G. Nature 480, 480–489 (2011).

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