A polymorphism in the cyp17 gene is associated with male breast cancer

SUMMARY The CYP17 gene codes for the cytochrome P450c17α enzyme that is involved in the synthesis of oestrogens. This case-control study from the South East of Scotland shows that a

polymorphism of the CYP17 gene is associated with an increased risk of male breast cancer. SIMILAR CONTENT BEING VIEWED BY OTHERS _CYP3A7*1C_ ALLELE: LINKING PREMENOPAUSAL OESTRONE AND

PROGESTERONE LEVELS WITH RISK OF HORMONE RECEPTOR-POSITIVE BREAST CANCERS Article Open access 26 January 2021 COMMON VARIABILITY IN OESTROGEN-RELATED GENES AND PANCREATIC DUCTAL

ADENOCARCINOMA RISK IN WOMEN Article Open access 27 October 2022 ASSOCIATION BETWEEN _CYP2E1_ POLYMORPHISMS AND COLORECTAL CANCER RISK: A SYSTEMATIC REVIEW AND META-ANALYSIS Article Open

access 23 November 2022 ARTICLE PDF CHANGE HISTORY * _ 16 NOVEMBER 2011 This paper was modified 12 months after initial publication to switch to Creative Commons licence terms, as noted at

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breast cancer susceptibility gene BRCA2. _Nature_ 378: 789–792. Article  CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * University of Edinburgh

Department of Pathology, Sir Alastair Currie CRC Laboratories, , Molecular Medicine Centre, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK I E Young, K M Kurian, C Annink, M L

Hooper & A H Wyllie * Department of Clinical Oncology, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK I H Kunkler * School of Biomedical Sciences, Bute Medical Building,

University of St Andrews, St Andrews, Fife, KY16 9TS, UK V A Anderson, B B Cohen & C M Steel * Department of Biology & Medical Laboratory Education, University of Professional

Education Enschede, Postbus 70000, Enschede, 7500 KB, The Netherlands C Annink * Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK A H Wyllie

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associated with male breast cancer. _Br J Cancer_ 81, 141–143 (1999). https://doi.org/10.1038/sj.bjc.6690663 Download citation * Received: 12 January 1999 * Revised: 10 February 1999 *

Accepted: 12 February 1999 * Published: 13 August 1999 * Issue Date: 01 September 1999 * DOI: https://doi.org/10.1038/sj.bjc.6690663 SHARE THIS ARTICLE Anyone you share the following link

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content-sharing initiative KEYWORDS * CYP17 polymorphism * male breast cancer