Elimination of the liquid junction by using glass electrodes

ABSTRACT IT is assumed in measuring potential with hydrogen or alkali-sensitive glass electrodes1 that the salt bridge which connects the reference electrode to the solution generates a

negligibly small potential at the liquid junction. This is a reasonable assumption so long as the unknown solution contains no colloids, and its ionic strength is approximately that of the

buffers used in standardization. Unfortunately these ideal conditions are seldom met in biological systems. The resultant error is often of a serious magnitude, as shown in experiments on

_p_H in colloidal systems2,3. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your

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FAQs * Contact customer support SIMILAR CONTENT BEING VIEWED BY OTHERS LABEL-FREE, NON-CONTACT DETERMINATION OF RESTING MEMBRANE POTENTIAL USING DIELECTROPHORESIS Article Open access 09

August 2024 SEARCH FOR A GROTTHUSS MECHANISM THROUGH THE OBSERVATION OF PROTON TRANSFER Article Open access 22 April 2023 NON-FARADAIC JUNCTION SENSING Article 09 December 2024 REFERENCES *

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AUTHORS AND AFFILIATIONS * Cardio-Pulmonary Laboratory, Mt. Alto V.A. Hospital, and Department of Medicine, Georgetown University, School of Medicine, Washington, D.C. CARL. R. MERRIL

Authors * CARL. R. MERRIL View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS

ARTICLE MERRIL, C. Elimination of the Liquid Junction by using Glass Electrodes. _Nature_ 192, 1087 (1961). https://doi.org/10.1038/1921087a0 Download citation * Issue Date: 16 December 1961

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