Effects of paludrine and other antimalarials

ABSTRACT THE facility with which pathogenic protozoa and A bacteria may acquire resistance to therapeutic agents, as a result of non-curative treatment of infections by these pathogens, is

of profound significance both for the theory and for the practice of chemotherapy. The readiness with which trypano-some species may thus develop resistance to certain types of compound is

well known; but malaria parasites in general have hitherto appeared singularly incapable of developing an acquired resistance, although a number of claims to have demonstrated this property

have been made. Only one of these claims, that of Fulton and Yorke1, referred to again below, can be incontrovertibly accepted. Access through your institution Buy or subscribe This is a

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EFFICACY AND MECHANISM OF RESISTANCE OF THE NOVEL CHEMOTYPE DDD01034957 Article Open access 21 January 2021 TOWARDS NEXT-GENERATION TREATMENT OPTIONS TO COMBAT _PLASMODIUM FALCIPARUM_

MALARIA Article 04 October 2024 GOSSYPOL IS A NATURAL PRODUCT WITH GOOD ANTIMALARIAL ACTIVITY AGAINST _PLASMODIUM FALCIPARUM_ CLINICAL ISOLATES Article Open access 09 January 2025 REFERENCES

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Google Scholar  * Curd, F. H. S., Davey, D. G., and Rose, F. L., _Ann. Trop. Med. Parasitol._, 39, 208 (1945). Article  CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS

AND AFFILIATIONS * Departments of Chemotherapy and of Entomology and Parasitology, Liverpool School of Tropical Medicine, J. WILLIAMSON, D. S. BERTRAM & E. M. LOURIE Authors * J.

WILLIAMSON View author publications You can also search for this author inPubMed Google Scholar * D. S. BERTRAM View author publications You can also search for this author inPubMed Google

Scholar * E. M. LOURIE View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS

ARTICLE WILLIAMSON, J., BERTRAM, D. & LOURIE, E. Effects of Paludrine and Other Antimalarials. _Nature_ 159, 885–886 (1947). https://doi.org/10.1038/159885a0 Download citation * Issue

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